IN most cases of familial methemoglobinemia, a hereditary defect exists in the major intraerythrocytic methemoglobin reducing mechanism, NADH methemoglobin reductase. 1 More than 200 patients with ...

The NADH methemoglobin reductase was assayed in all eight subjects by the method of Scott, 11 which measures the ability of hemolysate to reduce the dye dichlorobenzenoneindophenol.

The Fugates probably had a deficiency in the enzyme called cytochrome-b5 methemoglobin reductase, which is responsible for recessive congenital methemoglobinemia. Normally, ...

The main treatment for methemoglobinemia is methylene blue, which works as a cofactor for the NADPH methemoglobin reductase enzyme system to produce leukomethylene blue, which allows for the ...

According to ABC News, the Fugates most likely suffered from a deficiency in the enzyme known as cytochrome-b5 methemoglobin reductase, which causes recessive congenital methemoglobinemia.

The percentage of methemoglobin was 44%,” the ... patients with certain inborn deficits (ie, glucose-6-phosphodiesterase deficiency, hemoglobin-M disease, NADH-methemoglobin reductase ...

Patients at increased risk for methemoglobinemia include those with breathing problems (i.e., asthma, bronchitis, emphysema, smokers), heart disease, patients with certain inborn deficits (i.e ...

Furthermore newborns seem to be at a higher risk of developing methemoglobinemia due to a lower level of methemoglobin reductase and the fact that foetal haemoglobin is more easily oxidized.