In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
AZoLifeSciences on MSN2d
Understanding the Complex Architecture of the Minor SpliceosomeIn human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
In most eukaryotic cells, two types of spliceosome work in parallel to stitch gene pieces together: the major spliceosome and the minor spliceosome. The Galej Group at EMBL Grenoble has recently ...
the major spliceosome and the minor spliceosome. The Galej Group at EMBL Grenoble has recently published new structural insights into minor spliceosome function in the journal Molecular Cell.
Phys.org on MSN8d
The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA"However, analyzing the components flexibly bound to the periphery of the spliceosome was a major challenge for our work," ...
We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...
“However, analyzing the components flexibly bound to the periphery of the spliceosome was a major challenge for our work,” explains Dr Komal Soni from the BZH. Based on this structural ...
We study regulation of gene expression by the minor spliceosome. This parallel pre-mRNA splicing machinery functions during the nuclear RNA processing phase and regulates cellular mRNA levels. We ...
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