The major spliceosome is abundant in cells and has been extensively investigated for more than four decades. Its long-separated twin - the minor spliceosome, is much more scarce and remains enigmatic, ...

Most genes have many introns that belong to one class – the major introns – which are removed by the major spliceosome. However, around 0.5% of introns belong to another class – the minor introns – ...

The major spliceosome is abundant in cells and has been extensively investigated for more than four decades. Its long-separated twin – the minor spliceosome, is much more scarce and remains enigmatic, ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") -- and about 150 proteins, involved in different stages of ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") – and about 150 proteins, involved in different stages ...

The major spliceosome is abundant in cells and has been extensively investigated for more than four decades. Its long-separated twin – the minor spliceosome, is much more scarce and remains ...

A major lunar standstill is about to occur. The phenomenon happens every 18.6 years when the moon rises and sets at its most extreme points on the horizon, while also climbing to its highest and ...

The minor spliceosome excises ≈1 in 300 introns from human pre-mRNAs (11)—which encode proteins with a wide range of functions (12)—consistent with the lower abundance (≈1%) of its snRNPs relative to ...

An international research team has discovered a novel weak spot in prostate cancer cells, involving a component of the minor spliceosome that is significantly increased in advanced prostate cancer, ...

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

Briefly, the 5′ss and BPS are initially recognized either by separate U1 and U2 snRNPs (major spliceosome) or a U11/U12 di-snRNP complex (minor spliceosome). Additionally, the PPT and 3′ss in U2-type ...