In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
AZoLifeSciences on MSN20h
Understanding the Complex Architecture of the Minor SpliceosomeIn human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
"However, analyzing the components flexibly bound to the periphery of the spliceosome was a major challenge for our work," explains Dr. Komal Soni from the BZH. Based on this structural ...
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...
We study minor spliceosome which is a parallel pre-mRNA splicing machinery in the cells of most metazoan organisms. Our main aim is to investigate mechanism and regulation of this nuclear machinery, ...
“However, analyzing the components flexibly bound to the periphery of the spliceosome was a major challenge for our work,” explains Dr Komal Soni from the BZH. Based on this structural ...
We study regulation of gene expression by the minor spliceosome. This parallel pre-mRNA splicing machinery functions during the nuclear RNA processing phase and regulates cellular mRNA levels. We ...
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