The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Leishmaniasis is a life-threatening parasitic infection and one of the most concerning neglected vector-borne tropical diseases worldwide. Current leishmaniasis chemotherapeuticals are poorly ...

India is on track to be declared free of Kala Azar by 2024, achieving elimination targets set by WHO after decades of efforts against the deadly disease.

You have full access to this article via your institution. Interestingly, most individuals infected with Leishmania spp. develop strong and long-lasting protection against subsequent disease ...

Here, the authors show that the unusual chromosome size-dependent DNA replication timing in Leishmania is influenced by RNA-DNA hybrids that are recognised by the endonuclease RNase H1.

While there are many different kinds of sand flies, and not all are huge causes for concern, worry has arisen around the dangerous Leishmania parasite that they can carry. According to the World ...

Cutaneous leishmaniasis (CL) is a parasitic infection transmitted by sandflies, affecting millions worldwide. While the ...

Tropical diseases primarily affect people living in or visiting tropical and subtropical regions. Such disorders are major public health issues because they are usually caused by bacteria, viruses, or ...

However, epitopes containing 20 or less amino acids of Plasmodium falciparum and Leishmania donovani bind to multiple HLA-DR and MHC receptors. Thus synthetic epitope vaccines may better meet the ...

Nearly 1,300 probationary employees at the Centers for Disease Control and Prevention — roughly one-tenth of the agency’s ...