Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells
Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a ...
Supercomputers Help Unlock Secrets of DNA Repair
Researchers harness the power of the world’s most advanced supercomputers to simulate the inner workings of cellular ...
Nature15d
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair
by generating lethal DNA breaks during by transcription-coupled NER. Selection of Et743-resistant cell lines We generated two Et743-resistant derivatives of human colon carcinoma cells.
Frontiers21d
From gene modules to gene markers: an integrated AI-human approach selects CD38 to represent plasma cell-associated transcriptional signatures
The value of our AI-human hybrid framework extends beyond merely confirming known plasma cell markers. While our analysis did identify CD38, TNFRSF17, and IGJ as top candidates, their selection ...
Frontiers28d
Editorial: Failures and repairs in human-robot communication
we provide a platform for reporting commonly occurring communicative failures in human-robot interaction (HRI). Secondly, this topic aims to highlight the opportunity of potential multi-modal repair ...
Medical Xpress29d
Can melatonin supplements really 'reverse' DNA damage caused by lack of sleep?
The researchers then measured the repair of oxidative DNA damage by analyzing levels of a marker known as 8-hydroxy-2′-deoxyguanosine (8-OH-dG) in urine samples. Higher levels of this marker ...