Chromatin is a flexibly joined chain of nucleosomes that exists inside the ... The APC/C ubiquitylates histones to regulate gene expression in pluripotent cells. Here, the authors pair cryo ...
They successfully generated the HBV minichromosome for the first time, using their capabilities in reconstituting viral DNA in complex with human histones — which are ... into DNA-histone complexes ...
All histones were purified using the method described previously ... with biotin-14-dATP 72. The nucleosomes were assembled with the salt dialysis method 72. Purified DNAs were mixed with H3-H4 and ...
A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...
Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...
To clarify the association between certain immunologic factors and clinical activity in patients with systemic lupus erythematosus, 96 patients were studied. Those with antibodies to ...
The “Histones and Chromatin” Review series published in EMBO Reports and The EMBO Journal includes six reviews centered around the histone code hypothesis. The reviews focus on histone variants and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Single-Molecule Footprinting reveals that RNA ...
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States Native MS Guided Structural Biology Center, The Ohio State University, Columbus, Ohio 43210, ...
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