The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Genomic research holds incredible promise for improving human health, but one major challenge has slowed its progress: ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences ...

If you have an inherited intolerance to alcohol, a mutated gene could be the culprit. An at-home DNA test could detect whether you have the mutation, but doctors say there could be some drawbacks.

"For example, cancer researchers often use RNA sequencing techniques to compare gene expression in healthy versus cancerous cells," says Chao. Identifying splice sites is also important in annotating ...

Johns Hopkins researchers have developed a powerful new AI tool called "Splam" that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with ...

Alternative splicing (AS) is a genetic process that increases the diversity of proteins that can be generated from genes, by assembling sections of genetic code into different combinations.

The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of Health (grants R01GM130738, R01HG011067 ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that might be ...

By promoting splicing of exon 7, this drug (Spinraza) increased SMN expression in the cell from the SMN2 gene, compensating for the loss of SMN1, and preventing the loss of cells in the central ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs — single-stranded RNAs involved in protein synthesis — and proteins from the same stretch of DNA, plays ...