Using a genome-wide screen to look for single-nucleotide changes, the researchers found that the expression of a given gene -- the amount of protein it is producing -- can vary widely.

For example, the researchers were ... Assay of nearly 5,000 mutations reveals roots of genetic splicing errors. ScienceDaily. Retrieved May 29, 2025 from www.sciencedaily.com / releases / 2017 ...

Crucial differences between grafting, GMOs In “Genetic Modification is Really Nothing New,” (Times-Standard, Oct. 14, Page A4), Ruth Ramirez refers to “plant splicing” in wh… ...

A terrific article recently published in Molecular Biology and Evolution, "Alternative Splice in Alternative Lice," provides a compelling example of maximizing genome information – adaptation of ...

In what is perhaps the most striking example of alternative splicing complexity known, the single pre-mRNA for a Drosophila melanogaster axon guidance receptor gene, Down syndrome cell-adhesion ...

Gene duplication and alternative splicing are distinct evolutionary mechanisms that provide the raw material for new biological functions. We explored their relationships in human and mouse and ...

They also found that genetic variation leading to alternative splicing, a process that can create different proteins from the same gene, might in general be more relevant to disease than the ...

"For example, cancer researchers often use RNA sequencing techniques to compare gene expression in healthy versus cancerous cells," says Chao. Identifying splice sites is also important in annotating ...

The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of Health (grants R01GM130738, R01HG011067 ...

This diversity allows the observation of Asian-specific genetic regulation of splicing. For example, an sQTL of the TCHP gene has been identified to possibly influence the risk of Graves' disease ...

Gene Expression And Splicing Vary Widely From One Tissue To The Next Date: January 6, 2009 Source: Duke University Medical Center Summary: Genes talk to themselves and to each other to control how ...

Johns Hopkins researchers have developed a powerful new AI tool called "Splam" that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with ...