Researchers have uncovered how losing the autism-linked gene PTEN in a specific set of inhibitory neurons reshapes brain circuits tied to fear and anxiety.

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

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It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

The gene therapy also failed a key efficacy endpoint in the SRP-9001-102 study that led to its accelerated approval, as it was unable to outperform placebo in improving patients’ functional ...

Because of the ambiguous and subjective property of the facial expression, the label noise is widely existing in the FER dataset. For this problem, in the training phase, current methods often ...

Objectives To characterise the peripheral blood cell (PBC) gene expression changes ensuing from mycophenolate mofetil (MMF) or cyclophosphamide (CYC) treatment and to determine the predictive ...

Molecular imaging includes proteomic, metabolic, cellular biologic process, and genetic imaging. In a narrow sense, molecular imaging means genetic imaging and can be called molecular-genetic imaging.

This expression pattern was maintained up to HH stage 14 and thus overlapped with the onset of proepicardial marker gene expression (Figure 1C and 1G). 13,14,40 TWIST1 expression was particularly high ...