By replacing the defective gene associated with Dravet syndrome in mice, scientists successfully alleviated symptoms without ...

In a groundbreaking advancement for families grappling with the challenges of Dravet syndrome, a rare and life-altering form ...

Post-mortem examination of a mouse heart shows a clear delineation in blue where TREE gene enhancer sensed and responded to tissue damage of a heart attack. photo - Ken Poss Lab, Duke University ...

Although these non-coding regions do not encode proteins, they contain regulatory elements such as enhancer sequences, which play crucial roles in controlling gene expression. Enhancers can ...

In a groundbreaking advancement for families grappling with the challenges of Dravet syndrome, a rare and life-altering form ...

Researchers used powerful technology to analyse thousands of individual cells at once, considering which genes are active.

An international collaboration of researchers led by Masahito Yoshihara at Chiba University (Japan) has identified novel transcriptional enhancers that regulate gene expression in neuronal development ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...

Enhancers can also work independently of one another to direct composite patterns of gene expression when linked within a common region on the same DNA strand. Upon carrying out their study ...

Enhancer Biology lab studies gene regulation and genome architecture controlled by transcription factors using genome-wide functional genomics methods. Our aim is to understand enhancer malfunction ...