eLife3y
Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- ...
Frontiers5y
Insertion of LINE-1 Retrotransposon Inducing Exon Inversion Causes a Rotor Syndrome Phenotype
The pET-01 vector was used for both exon-trapping and as a splicing reporter. The wild-type or inverted exon 4 and the flanking intronic sequences (250 bp) were cloned into the pET-01 vector using ...
eLife6y
Arabidopsis RNA processing factor SERRATE regulates the transcription of intronless genes
Accurate gene expression at the level of RNA processing includes various steps, including the attachment of a 7-methylguanosine (m 7 G) cap to the 5ʹ end (capping) of the nascent mRNA, followed by ...