Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of ...

Transposons, so-called jumping genes, are a threat to genomes, so plants work hard to prevent them from mobilizing and ...

Researchers at Fred Hutch Cancer Center have discovered an overlooked mechanism driving aggressive breast and brain tumors ...

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has just been completed and released on a new website. For ...

Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo ...

Or humans. Manipulating genes to correct diseases or improve crops are not new ideas. But (especially in medicine) earlier technologies struggled due to being unsafe or prohibitively cumbersome.

All of this has resulted in a sour business mood, and a number of gene-editing therapy companies are struggling to stay afloat. Some have dramatically narrowed their pipelines and laid off staff.

The preprint also presented a workflow for “generative epigenomics,” which designed DNA sequences with desirable chromatin accessibility profiles to simulate eukaryotic gene regulation.