Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Stimulator of interferon genes (STING) is ...

This important study explores the commander-independent function of COMMD3-Arf1 in endosomal recycling. The evidence supporting the authors' claims is solid; however, the inclusion of additional ...

Giamundo et al. present fundamental data with new insights into the role of Ezrin, a major membrane-actin linker that assembles signaling complexes, in the spatial regulation of EGF signaling ...

Rab5 effectors, such as early-endosome antigen 1 (EEA1) and rabankyrin-5, bind not to Rab5-GDP, but to Rab5-GTP; thus a key determinant of Rab5 function is the duration of the GTP-bound state (3–5).