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Synthesis method unlocks a pathway to valuable fluorinated drug compounds for new medicines
In this vein, isosteric replacement of a CH 2 unit within an oxetane (or C=O group within a β-lactone) with CF 2 results in α,α-difluoro-oxetanes, a prized class of heterocyclic compounds with ...
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New Technique Yields Key Fluorinated Drug Compounds
In this vein, isosteric replacement of a CH 2 unit within an oxetane (or C=O group within a β-lactone) with CF 2 results in α,α-difluoro-oxetanes, a prized class of heterocyclic compounds with ...
C&EN1mon
Harnessing the Efficiency of Twin Boron Nitride and Graphene Monolayers for Anticancer Drug Delivery: Insights from DFT
Condensed Matter Theory Group, Materials Theory Division, Department of Physics and Astronomy, Uppsala University, Box 516, Uppsala 75120, Sweden ...
C&EN1mon
Enhancing Electron Donor–Acceptor Complex Photoactivation with a Stable Perylene Diimide Metal–Organic Framework
Department of Chemistry, The University of Hong Kong, Hong Kong 999077, P. R. China Department of Chemistry, The University of Hong Kong, Hong Kong 999077, P. R. China State Key Laboratory of ...
Frontiers3y
A Systematic Study of the Mechanism of Acacetin Against Sepsis Based on Network Pharmacology and Experimental Validation
Acacetin (MedChemExpress, molecular weight: 284.26 g/mol), LPS (Sigma, 055:B5, L2880), and Gap27 (MedChemExpress) were used in the experiments. The lung and liver tissues were collected and fixed in a ...