This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

Abstract: 3D phase contrast microscopy is one of the most common imaging modalities for the observation of long-term multicellular processes of living cells without phototoxicity and photobleaching, ...

THE detail seen in a highly magnified electron micrograph is to-day limited more by a lack of contrast in the image than by any lack of resolution in the microscope, which is now usually capable ...

Images were taken under the Leica TCS SP5 confocal laser microscope with ×63 objectives. The intensity of the MitoSox fluorescence signals per cell was quantified by Leica X Life Science Microscope ...

Here we present a set of technologies in embryos and cells, including IRES-mediated translation of circular RNA (circRNA) reporters, single-molecule messenger (m)RNA isoform imaging, PacBio long-read ...

This continuous replication coupled with gene expression and the resultant evolution are fundamental functions of living things, but they have not previously been reconstituted in cell-free systems.

which may be subject to interference by illumination artifacts. In particular, the so-called vignetting artifact—the decrease of image intensity toward the edges of an image—is, at the moment, widely ...

Neurons were visualised with an infrared differential interference contrast (DIC) microscope using a 40x water-immersion objective. Hippocampal subfields were identified and whole-cell patch-clamp ...