Cruciferous plants' pungent defense mechanism: How repurposed stomatal genes also fend off herbivores
Throughout evolution, plants have continuously adapted to survive in changing environments. Apart from complex structural ...
EMBO Press2d
HDAC6 deacetylates ENKD1 to regulate mitotic spindle behavior and corneal epithelial homeostasis
HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...
eLife13d
Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...
eLife17d
Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions
Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...
Medical Xpress28d
FDA recognizes need for immunogenicity assays in therapeutics with carriers or conjugates
After fixation with paraformaldehyde, cells were incubated with a 1:2,000 dilution of anti-PS monoclonal antibody clone PS05 (green) in PBS followed by counterstaining of nuclei with DAPI (blue ...