BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment options remain limited. The HFpEF syndrome is associated with a high ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

The team from The Florey and University of Melbourne focused on somatic mutations, which are not inherited, but occur over time in cells during aging. Mutations can disrupt a cell's normal ...

Using endothelial colony-forming-cells (ECFC), we have demonstrated accelerated senescence in smokers and patients with COPD compared with non-smokers. Subgroup analysis suggests that ECFC from ...

After fixation with paraformaldehyde, cells were incubated with a 1:2,000 dilution of anti-PS monoclonal antibody clone PS05 (green) in PBS followed by counterstaining of nuclei with DAPI (blue).

and DAPI (C1006, Beyotime, Shanghai, China) was used for nuclear staining. The cell morphology was observed using an inverted fluorescence microscope. The experimental animals were randomly divided ...

m 6 A RNA modification has been linked to regulation of osteogenic differentiation. This study defines the RNA m 6 A methylome of skeletal cell populations and reveals the role of METTL3-dependent ...

The large, purple-stained cell in the center of the image is a monocyte, a type of white blood cell The researchers then conducted a control experiment to “probe the interplay between sleep ...

The attached cells were stained by MemGraft-Cy3 or MemGraft-Cy5 as described ... light source Lumencor SOLA III equipped for exciting light in 5 different channels (DAPI, GFP, Cy3, Cy5 and transmitted ...