Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

Understanding the replication and transcription processes of mtDNA ... (2025) TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA.

Nowadays, advanced research techniques used in virological researches have greatly promoted the identification of RTC components and molecular interactions involved in the RNA genome replication and ...

This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

such as HEXIM1 and MePCE are believed to be essential for LARP7 to regulate transcription. We subsequently evaluated the binding affinity of LARP7 mutants to 7SK snRNA by using RNA immunoprecipitation ...

For transcription, a solution containing 2 μM of the double-stranded DNA, 6.25 mM rNTP, 80 mM HEPES-KOH pH 7.5, 24 mM MgCl 2, 2 mM spermidine, 40 mM DTT, 20 μg/mL pyrophosphatase (Roche) and a ...

The effect of saccharin on the microbiome has received much attention, but its impact on pathogenic bacterial species is less ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...