In this webinar, Brian Hie will discuss Evo2, a state-of-the-art genomic foundation model capable of generalist prediction ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

In a big leap for genomics, Google on Wednesday unveiled a powerful AI model that predicts how single DNA mutations affect the complex machinery regulating gene activity. Named AlphaGenome, the tool ...

This review focuses on the unique characteristics of mitochondrial nucleoids in mammalian cells, highlighting their semi-autonomous nature and the ...

To understand how this looping eventually gives rise to rod-shaped chromosomes, the researchers built a computational model based on two simple assumptions. First, as observed, DNA forms ...

The new AI model, ChromoGen (CHROMatin Organization GENerative model), can quickly analyze DNA sequences and predict the chromatin structures that those sequences might produce in a cell.

Evo is a large language model that is not trained on words but on the genomes of millions of microbes. It can accurately predict the effects of mutations.

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

In a unified model, cohesin sequentially captures two DNAs to establish sister chromatid cohesion at DNA replication forks and chromatin loops at places of transcription.