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Slow editing of protein blueprints leads to cell death, spliceosome study discoversMore information: Cristian Prieto-Garcia et al, Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy, Science (2024). DOI: 10.1126/science.adi5295 ...
Although in many cases adjacent exons are joined during the splicing reaction, in some cases exons can be skipped or cryptic splice sites activated, resulting in alternatively spliced transcripts.
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