HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

The normal cornea is devoid of lymph vessels ... cells leads to in-growth of lymph and blood vessels. Largely CD4 T-cell mediated immunopathology, although many other immune cells, including ...

Surgeons restored corneal surfaces in the injured eyes of 14 patients in a small clinical trial. Stem cells from each patient’s healthy eye were cultivated in a lab to grow healthy tissue that could ...

Novel stem cell therapy repairs 'irreversible' corneal damage in clinical trial Date: March 4, 2025 Source: Mass Eye and Ear Summary: Results from a phase 1/2 clinical trial of a novel stem cell ...

A new stem cell therapy has repaired blinding damage to the cornea in 93% of patients in an early clinical trial. However, severe injuries, such as those caused by chemical burns or infections ...

Sudden onset of pain, photophobia, discharge and reduced vision in a patient with an inflamed eye and opacity on the cornea is suggestive of a corneal ulcer. The differential diagnosis of a ...

Results also showed significant improvements in corneal staining and tear production, with effects observed as early as week 4 and maintained through week 12. Patients reported reduced reliance on ...

The RESTORE VISION scientific team has identified seven rare ocular conditions that impact the cornea and the rest of the ocular surface. "With a comprehensive approach, we aim to restore the ...

Two pivotal phase 3 clinical trials showcased the ability of acoltremon 0.003% to improve conjunctival and corneal staining in patients with dry eye disease. Topical acoltremon 0.003% significantly ...