Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key ...

The findings of two recent studies give hope that the disease could one day be reversed in humans—but experts warn that this ...

An overactive LRRK2 enzyme causes cells to lose their primary cilia, a cellular appendage that acts like an antenna, sending ...

The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.

Putting the brakes on an enzyme might rescue neurons that are dying in Parkinson's disease, stabilizing the progression of ...

By shutting down a hyperactive enzyme, scientists got damaged brain cells to regrow their lost “antennae” and restart ...

Some types of cancer cells appear to use some ciliary molecules so that instead of performing their normal functions, they begin to promote tumor formation and growth by activating biochemical ...

Too much LRRK2 in the brain changes the structure of cells by causing them to lose their "antenna" (technically the primary cilia) that allows them to send and receive chemical messages.

Jim FessendenUMass Chan Medical SchoolNew research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome ...

Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a ...

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...