The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key ...

A team of scientists, led by Dr. Helen Willsey from University of California, San Francisco, U.S., discovered that tiny hair-like structures called cilia, found on the surface of almost every cell, ...

Now, in a recently published Journal of Cell Biology paper, scientists used a newer electron microscopy technique, called volume electron microscopy (vEM), to examine how primary cilia on developing ...

Many cells in our body have a single primary cilium, a micrometer-long, hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating ...

A new study from Stanford Medicine has found that stopping an overactive enzyme in the brain might help protect and even ...

Restoring the signal Further experiments showed that restoring C21orf2 levels in mutated cells repaired the cilia defects, restored Shh signaling, and rescued neuromuscular junction formation.

Published in Nature Communications, the study describes how two key proteins allow glial cells to actively monitor the hair-like cilia that extend out of nematode dendrites, so that the glial ...

Dysfunctions of the tiny cell processes (primary cilia*) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An ...

Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a ...

New research from the University of Osaka has uncovered how air pollution impairs the lungs' self-cleaning system by damaging cilia on airway cells. The study also identifies a potential treatment ...