In order to better understand these extreme phenotypes, researchers evaluated pre-treatment tumor and germline samples from patients with advanced clear cell RCC treated with immunotherapy-based ...

(UroToday.com) The 2025 American Society of Clinical Oncology (ASCO) Genitourinary (GU) Annual Symposium held in San ...

Reprinted with permission from Shen T, Miao S, Zhou Y, Yi X, Xue S, Du B, et al. Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor ...

and its expression is suppressed in various tumor cells. However, whether it participates in the immune response in kidney renal clear cell carcinoma (KIRC) is unknown, and the defined mechanism is ...

thereby delivering targeted radiation to cancer cells in the body with minimal damage to surrounding healthy cells: Up to 100 patients with treatment naive, biopsy-proven clear cell RCC with adequate ...

Groundbreaking findings from the landmark CLEAR (Clinical trial Comparing Lenvatinib with Ecerolimus or Pembrolizumab in ...

Casdatifan targets a transcription factor that binds with other proteins to switch off the body’s anti-inflammatory mechanisms, empowering genes that promote tumor growth in clear cell renal cell ...

Cancer cells have recently been shown to collaborate to obtain vital nutrients from their environment, a phenomenon that was ...

Dr. Katy Beckermann discusses how a Fotivda and Opdivo combination for renal cell carcinoma compared with Fotivda alone based ...

Changes in tumor size track outcomes for patients with advanced renal cell carcinoma (aRCC), according to new data from the landmark CLEAR study being presented this week at the 2025 American ...

papillary RCC and chromophobe RCC. Metabolic dysregulation in the development of clear cell renal cell carcinoma (ccRCC) remains to be understood. Here the authors identify that a carnitine ...

Thomas Hutson, DO, PharmD, discusses key takeaways from the phase 3 CLEAR trial evaluating lenvatinib plus pembrolizumab in ...