LIVMARLI is the first and only treatment available for cholestatic pruritus in patients with Alagille syndrome and ...

Mirum Pharmaceuticals’ MIRM lead product, Livmarli (maralixibat), an orally administered ileal bile acid transporter (“IBAT”) ...

In liver disease, itching can signal a more complex health concern, particularly in conditions such as primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and intrahepatic ...

Pregnancy-specific skin conditions: Certain pregnancy-related skin conditions, like rashes or bumps, can trigger itching. An example is intrahepatic cholestasis of pregnancy (ICP). This liver ...

Itchy skin, or pruritus, can result from conditions like eczema or dermatitis. Less commonly, it can stem from conditions such as kidney failure and liver disease. Some causes of itching affect ...

Specific dermatoses of pregnancy, according to the reclassification by Ambros-Rudolph et al. 8. Ambros-Rudolph et al. described two clinical presentations: the eczematous type (E-type) with a classic ...

Sometimes, it may be a symptom of an underlying condition. Itchy skin at night, called nocturnal pruritus, can be severe enough to disrupt sleep regularly. Why this happens can range from natural ...

Cholestasis is a condition in which the flow of bile from the gall bladder to the duodenum is impaired. The condition can result from obstruction of the extrahepatic or intrahepatic bile ducts ...

Someone may experience itching around the vulva and vagina for several possible reasons. For example, vaginal itching or irritation may be due to contact with fabrics or scented soaps, yeast ...

LIVMARLI approved by the FDA for cholestatic pruritus in progressive familial intrahepatic cholestasis (PFIC) patients 12 months and older and in Europe for treatment of PFIC in patients three ...