1 Aortic stenosis is generally well tolerated for a prolonged period of time, even when the condition is severe, despite the increase in left ventricular afterload caused by the constricted outflow.

The patient with severe aortic stenosis is relatively "afterload fixed and preload dependent" -- meaning cardiac output does not increase with after-load reduction. Thus all afterload reducing ...

They conclude: ‘the concept of chronic MR as a disease of pure high-preload and low-afterload is misleading. Afterload is actually normal or above normal in chronic phases of the disease. In addition ...

Elucidation of the (human) Starling curve by Sarnoff, ejection fraction by Braunwald, principles of backward and forward failure generating paradigmatic hemodynamic considerations of preload and ...

Because the potential cardiac complications of COVID-19 were unknown at the time of her presentation, we chose to avoid the potential risks of haemodynamic collapse associated with afterload reduction ...

It’s about knowing why a heart failure patient should be treated with afterload reduction. It’s appreciating that hypoxic respiratory failure is best treated by increasing alveolar pressure ...

While a normal MAP in adults ranges from 70 to 105 mmHg, LVADs do not function optimally against higher afterload, so mean pressures of less than 90 are often desirable. Clothing, patient access ...