As a result of subcellular gradients in forces and material properties, actin flows rapidly rearward in the growth cone periphery, and microtubules flow forward in bulk along the axon. With this ...

This study provides important insights into how IL-1 cytokines protect cells against SARS-CoV-2 infection. By inducing a non-canonical RhoA/ROCK signaling pathway, IL-1beta inhibits the ability of ...

To explore potential cytoskeletal or cell shape regulation of RELA in PDAC, we constructed Bayesian models using single-cell datasets from TNFα-stimulated PDAC cells with variation in RELA, actin, and ...

Here, the authors have identified a mutation in the gene GNA13 in patients with hypomelanosis of Ito and developmental anomalies, which triggers excessive RHOA/ROCK signaling and actin ...

suggested that the generated tubulin images were more similar to the truth tubulin images than to the actin filament images. With the development of statistics for image comparison, as well as the ...