New method for selective protein modification in living systems could advance cancer research
A research team has developed an innovative technique that enables precise modification of specific proteins within complex ...
Medscape2d
Clues for the Obstetrician-Gynecologist
In the dipstick method, neutrophilic esterases catalyze the hydrolysis of esters to produce their respective alcohols and acids. The alcohols produced then react with a diazonium salt to produce a ...
Scientific Research Publishing9d
Novel Synthetic Method for the Vilsmeier-Haack Reagent and Green Routes to Acid Chlorides, Alkyl Formates, and Alkyl Chlorides ()
2.2. Examples of Synthesis of Acid Chlorides Using the OPC-VH Reagent Acid chlorides are important synthetic intermediates for the preparation of esters and amides ... in solution and subsequently ...
Science Daily8d
Revolutionizing protein modification: A new frontier in cancer research
A research team has developed an innovative technique that enables precise modification of specific proteins within complex biological environments.
EMBO Press13d
A new hybrid post-translational modification—have you lost your (MARUb)les?
Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...
MPR12d
Gerty Cori: Her Life and Career
Gerty Theresa Cori (1896-1957) was a trailblazing biochemist whose work fundamentally reformed our understanding of how cellular energy is stored and ...
EurekAlert!8d
Revolutionizing protein modification: a new frontier in cancer research
They developed a technique that combines deoxyoxanosine (dOxa) with aptamers, nucleic acid-based molecular recognition ... biomodification reagents (NHS ester), remaining stable for over a month ...