Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

Much effort was expended on the comprehension of the structure and dynamics of this complex machine during the splicing process, but the rules that discriminate introns and exons within the message ...

Its long-separated twin - the minor spliceosome, is much more scarce and remains enigmatic, even though its function is equally important. In this new study, the researchers reveal the structure of ...

In this new study, the researchers reveal the structure of U11 snRNP – one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together ...

Its long-separated twin – the minor spliceosome, is much more scarce and remains enigmatic, even though its function is equally important. In this new study, the researchers reveal the structure of ...

In this new study, the researchers reveal the structure of U11 snRNP -- one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

“Understanding the function and the structure are very different. The structure is a stable image in perfect conditions, but perfect conditions do not exist in our body. Understanding how the ...

These findings not only advance our understanding of spliceosome function but also open potential opportunities to target RNA processing for therapeutic interventions in diseases associated with ...