The U1 snRNP complex ensures that the protein blueprints are fully completed. This is important because cells tend to halt the process prematurely. This type of quality control, so-called ...
Spliceosomes are large and dynamic RNA-protein complexes ... the researchers obtained the structure of the U11 snRNP complex and revealed how it recognizes the "5' splice site"—the starting ...
The HIV-1 Tat protein promotes viral transcription elongation by recruiting P-TEFb to RNA element TAR on the viral mRNA. Recent work from D'Orso and Frankel uncovers unexpected aspects of this ...