Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

During the first step of converting genetic information into functional proteins, cells transcribe the double-stranded helix ...

News & Views Published: December 2008 Short-circuiting RNA splicing Matthew D Disney Nature Chemical Biology 4, 723–724 (2008) Cite this article ...

mRNA vaccines work differently: The antigen is produced inside the body. The vaccine itself consists of a small piece of genetic code—messenger RNA (mRNA)—to which the immune system responds.

Dynamics are intrinsic to both RNA function and structure. Yet, the available means to precisely provide RNA-based processes with spatiotemporal resolution are scarce. Here, our work pioneers a ...

Lipid nanoparticles (LNPs) have shown great promise for nucleic acid drug delivery. Canonical LNPs consist of four lipid components: ionizable lipid, cholesterol, Polyethylene glycol-yl-lipid ...

Barcelona-based genetic medicines company SpliceBio has raised $135 million in a series B round to back its novel protein-splicing drug delivery system, the biotech announced Wednesday. The money will ...

A new kind of cancer treatment is emerging—one that turns the patient’s own body into a drug factory. In a pioneering first-in-human trial presented at the 2025 American Society of Clinical Oncology ...