This cover highlights the article A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung diseasee by Kyungtae Lim, ...
As a pivotal regulator of 5’ splice site recognition, U1 small nuclear ribonucleoprotein (U1 snRNP)-specific protein C (U1C) regulates pre-mRNA splicing by interacting with other components of the U1 ...
A U2 snRNA mutation causes neuron degeneration ... linked to both ALS and frontotemporal dementia (FTD), interacts and interferes with U2 snRNP. In patient derived cells, this led to mislocalisation ...
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