Since 2002, PNAS has offered free and immediate access to journal content for researchers in an initial group of 81 countries, a number that has grown to over 120 lower-income countries. This access ...

A kidney cancer cell nucleus is studded with aberrant nuclear speckles (orange). Normal healthy cells tend to have the speckles clustered toward the middle. Image credit: Kate Alexander (Cold Spring ...

The rates of biological primary production before the emergence of atmospheric oxygen on Earth are thought to be low. However, mudstones from the Archean Era contain a high organic matter content, ...

In 2010, climate scientists gathered at the Asilomar Conference Center in California, in a convening that echoed a legendary 1975 meeting in which a scientific committee came together in a exercise of ...

High-resolution measurement of Roman-era lead pollution in Arctic ice cores at the Desert Research Institute. Image credit: Jessi LeMay (Desert Research Institute, Reno, Nevada). Atmospheric lead ...

In the summer of 1977, Yosef Shiloh, then a graduate student, visited an Israeli Moroccan Jewish family with several children affected by ataxia-telangiectasia (A-T), a rare and complex genetic ...

Since the turn of the 21st century, rapid advancements in phylogenomics have significantly deepened our understanding of the tree of life, particularly for ancient divergence. A recent letter to the ...

Cable bacteria (Desulfaobulbaceae) are known for their ability to conduct electricity in the form of negatively charged electrons over many millimeters. To determine whether cable bacteria can also ...

Long before the election cycles of 2024, 2020, or even 2016, anyone who followed US political news could sense it—a toxic, ever-escalating tide of alienation, suspicion, and loathing for the opposing ...

In PNAS, Mughal et al. describe a mechanism—termed electro-Ca 2+ coupling—that links electrical and Ca 2+ signaling in ECs and has implications for the control of cerebral blood flow. This work was ...

Maria Iandolo New, who passed away on July 26, 2024, at the age of 95, was the child of Italian immigrants who came to America as professional musicians. She grew up in the Little Italy section of ...