It’s the Purdue Boilermakers vs Houston Cougars in March Madness bracket. Here’s our prediction for the 2025 NCAA Tournament Sweet 16 game.

Purdue put away No. 12 seed McNeese State early in the NCAA Tournament's second round in Providence, R.I. Now the Boilermakers get to play in Indiana.

The Boilermakers had heard plenty about High Point's depth and its bench. But it was Purdue's bench that made the different in the first round of NCAA Tournament.