Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...
The FDA has approved Evrysdi in tablet form for patients with spinal muscular atrophy aged 2 years and older who weigh more ...
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
The 5 mg risdiplam tablet provides the same efficacy and safety for spinal muscular atrophy as the currently available oral ...
News Medical on MSN2d
EMBL researchers reveal new structural insights into minor spliceosome functionIn human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...
AZoLifeSciences on MSN18h
Understanding the Complex Architecture of the Minor SpliceosomeIn human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...
AZoLifeSciences on MSN4d
High-Resolution Images Reveal How Cells Discard Faulty SpliceosomesA sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into ...
HNRNPC, known for its role in pre-mRNA splicing, was found to enhance the inclusion of BOLA3 exon 3, leading to increased BOLA3 protein levels and promoting ESCC cell proliferation, migration ...
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