Researchers from Tel Aviv University and the Israel Institute for Biological Research in Ness Ziona have used the platform ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...

Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Researchers from China recently reported that it’s hard to make sense of the widespread persistence of A-to-I mRNA editing in animals Published - May 19, 2025 05:30 am IST ...

Ultimately, we selected eight candidate variants to assess their effects on pre-mRNA splicing. The numbering of DNA variants is based on the complementary DNA (cDNA)sequence of CFTR (Ref Seq NM_000492 ...

Utilising Ribopro’s mRNA sequence optimisation and lipid nanoparticle-based delivery expertise alongside IPA’s single-cell analysis, B-cell screening and deep-learning AI-powered discovery workflows, ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

Nuclear pre-mRNA half-life showed the narrowest distribution, ranging from 10 to 46 min (10th and 90th percentile, resp.) with a median of 22 min. Cytosolic transcript half-lives displayed the widest ...

On average, it outperformed standard pre-training methods by 8% in predictive tasks across six diverse datasets. For example, in antibody mRNA sequence annotation, HELM achieved an accuracy ...

The FDA approved mRNA-1345, a Moderna vaccine for the treatment of respiratory syncytial virus (RSV). This single-dose vaccine offers protection against lower respiratory tract disease in adults ...