Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Jamie-Lynn Sigler is reflecting on the scariest time in her life when her 11-year-old son Beau was hospitalized with a life-threatening autoimmune condition last summer. “Those were the hardest ...

Some seven months after her son Beau was hospitalized for 33 days with a rare autoimmune condition, Jamie-Lynn Sigler is now sharing some of the harrowing details of his fight for life.

The "Dead to Me" star shared the toll that multiple sclerosis has taken on her body and digestive system since she was diagnosed in 2021.

The 'Married With Children' actress shared an honest update with listeners on her podcast about her ongoing health battle.

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else,” the “Dead ...

Christina Applegate revealed she's been hospitalized more than 30 times in three years since being diagnosed with multiple ...

The Sopranos' actress Jamie-Lynn Sigler, 43, remembers nights when she ‘fell apart, terrified’ fearing her son Beau 'was going to die' after he was diagnosed with acute disseminated encephalomyelitis, ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

Jamie-Lynn Sigler has learned to live with pain since being diagnosed with multiple sclerosis when she was 20 — but nothing prepared her for the kind of anguish she faced last summer when her 11 ...