imdb.com18d
Splice: Why The Sci-Fi Horror Movie's Sequel Never Happened
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Frontiers26d
Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation
XBP1 mRNA splicing was detected by reverse transcription (RT)-PCR using the following set of primers: Forward 5′-CTGAAGAGGAGGCGGAAGC-3′ and reverse 5′-AATACCGCCAGAATCCATGG-3′, which recognize both the ...
eLife6y
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1
The protein folding capacity of the endoplasmic reticulum (ER) is tightly regulated by a network of signaling pathways, known as the unfolded protein response (UPR). UPR sensors monitor the ER folding ...
Frontiers6y
Computational Tools for Splicing Defect Prediction in Breast/Ovarian Cancer Genes: How Efficient Are They at Predicting RNA Alterations?
In silico tools for splicing defect prediction have a key role to assess the impact of variants of uncertain significance. Our aim was to evaluate the performance of a set of commonly used splicing in ...