Japanese scientists pioneer nonviral gene delivery in primates
Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a ...
CURE6d
Gene Expression Testing and Targeted Therapies in Breast Cancer Care
Gene expression testing helps determine chemotherapy needs for hormone receptor-positive breast cancer, optimizing treatment ...
One-step creation of Cre-loxP organisms: Precise control and modification of gene expression
Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...
Analyzing genetic 'signatures' may give insight into what stresses wild bees
A new method of examining gene expression patterns called landscape transcriptomics may help pinpoint what causes bumble bees stress and could eventually give insight into why bee populations are ...
The American Journal of Managed Care6d
EMBARK Data Show Continued Improvements With DMD Gene Therapy
Data from the EMBARK trial of delandistrogene moxeparvovec in patients with Duchenne muscular dystrophy (DMD) show that ...
eLife1d
Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability
The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...
Healio12d
Q&A: ‘An exciting breakthrough’: Gene transfer therapy promising in Danon disease
Danon disease is a rare but serious cardiomyopathy that drastically reduces life expectancy. Male patients infrequently live ...
Study Finds on MSN1d
What Did Dinosaur Feathers Look Like? Scientists May Have Recreated Them in Chickens
Explore the fascinating world of dinosaur feathers and their evolution through groundbreaking research on chicken embryos.
National Audubon Society1h
North Carolina’s Cape Fear River Is a ‘Forever Chemical’ Hotspot—What Does That Mean for Its Birds and People?
Amid mounting global health concerns about PFAS, communities living along the waterway must grapple with how contamination is ...
eLife12d
Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...