Normal red blood cells are in the shape of a disk, thicker on the edge and thinner in the middle ... Treatment can be long-term for poikilocytosis caused by sickle cell disease or thalassemia.

Learn what causes sickle cell thalassemia, a milder form of sickle cell disease. ... But sickle hemoglobin tends to devolve into a rigid crescent shape, deforming and damaging your red blood cells.

Thalassemia is a genetic blood disorder that impacts the ability of the blood to get oxygen to the body’s organs. Learn about the signs, how it’s diagnosed & treated.

Several red blood cell disorders can decrease the effectiveness of a person’s red blood cells. These include anemia, polycythemia, sickle cell disease, thalassemia, and malaria.

In Thalassemia, , these alpha or beta proteins are not produced enough leading to break down of red blood cells and causing anemia. The affected child will have anemia at an early age and have ...

The European Union on Tuesday approved the world’s first medicine based on CRISPR gene-editing technology to treat two blood disorders, following the U.S. and U.K. in a milestone for the ...

For the first time, U.S. regulators have cleared a treatment using CRISPR, the gene-editing technology, for patients. The product is Casgevy, a treatment for sickle cell disease and beta ...

Called Casgevy, the gene-editing treatment is for people with sickle cell disease and a related blood disorder called beta thalassemia. UK regulators approved the treatment in November 2023 ...

The treatment, called exa-cel and made by the companies Vertex and CRISPR Therapeutics, edits a gene involved in red blood cell shape and function. It appears to functionally cure the disease for ...

A Northeast Ohio woman and a 22-year-old man from UAE are among the first patients to receive the innovative CRISPR treatment.