Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...

Maturation of snRNAs, key parts of the spliceosome, involves nuclear export of newly synthesized snRNAs to the cytoplasm. PHAX is known to mediate snRNA export in a phosphorylation-dependent ...

DNA templated’, and ‘U2-type precatalytic spliceosome’. These results in module E indicate that there is a sexually dimorphic gene expression program broadly distributed across the finch telencephalon ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

Modifications in proteins after they are synthesized (post-translational) are changes that play a fundamental role in cell ...

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

This useful study presents a biologically realistic, large-scale cortical model of the rat's non-barrel somatosensory cortex, investigating synaptic plasticity of excitatory connections under varying ...

Senate Begins Passage of Stablecoin Bill as House Marks Market-Structure Wins The U.S. Congress is in the thick of its crypto efforts this week, with the Senate starting on final votes to approve ...

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

Synopsis Disrupting the expression of the minor spliceosome component RNPC3 reduces the growth of oncogene-driven cancer cells in a broad spectrum of tumours. Targeting the minor spliceosome may ...