Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...

are one of the main causes of inheritable genetic disorders and are associated with neurodevelopmental disorders and diseases such as cancer. It was known that the spliceosome has quality control ...

Proper splicing requires efficient spliceosome assembly ... A mechanistic study reveals that RBPMS suppresses bladder cancer cell migration by regulating alternative splicing of ANKRD10, which ...

MYB acts as a master regulator of cell proliferation, self-renewal, and differentiation processes and its aberrant expression has been demonstrated in multiple forms of human cancer including ...

The fit between a splice site and the spliceosome components that bind it influences splicing activity. Strong splice sites closely match consensus sequences and are efficiently recognized by the ...

This spliceosome is made up of variety of protein ... because defective splicing is associated with various diseases, among them cancer as well genetic and neurodegenerative diseases,” explains ...