Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...
It also changes in size during childbirth. For most people, variations don't affect function but procedures like dilation may be needed in people who have had vaginoplasty surgery to create or repair ...
Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Rd., Shanghai 201203, China State Key Laboratory of Drug Research, Shanghai ...
1State Key Laboratory of Molecular Oncology, SXMU-Tsinghua Collaborative Innovation Center for Frontier Medicine, School of Basic Medical Sciences, Tsinghua University, Beijing, China. Search for ...
In general, by leveraging bioinformatics analysis followed by experimental substantiation, we elucidated the prospective function and predictive value of EFTUD2 in LUAD, indicating that EFTUD2 is a ...
Background: Cystic fibrosis (CF) is a common monogenic multisystem disease caused primarily by variants in the CFTR gene. Emerging evidence suggests that some variants, which are described as missense ...
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