The Galej Group at EMBL Grenoble has published new structural insights into minor spliceosome function in ... The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") – and about 150 proteins, involved in different stages ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") – and about 150 proteins, involved in different stages ...

The spliceosome uses numerous strategies to regulate its function in mRNA maturation. Ubiquitin regulates many cellular processes, but its potential roles during splicing are unknown. We have ...

The major spliceosome consists of five subunits, U1, U2, U4, U6, and U5 small nuclear ribonucleoprotein particles (snRNPs, read "snurps") -- and about 150 proteins, involved in different stages of ...

The U5 snRNP functions in spliceosome assembly as a part of either the U4/U6-U5 triple snRNP or a supramolecular holoenzyme containing all five snRNPs, the penta snRNP 5.The yeast U5 snRNP 6 ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome ...

Mechanism discovered that protects tissue after faulty gene expression Date: February 2, 2024 Source: University of Cologne Summary: A study has identified a protein complex that is activated by ...

Their findings reveal that spliceosome subunits U4, U5 and U6 are normally stabilized as a complex by a protein called USP39. However, ... a function that USP39 provides.

Team finds how a key enzyme of the spliceosome exerts its controlling function. by Freie Universitaet BerlinFreie Universitaet Berlin ...

Spliceosome assembly in yeast extracts also could occur by interaction of the U1 snRNP with the pre-mRNA, followed by a tetra-snRNP joining to form a functionally identical particle. (Reprinted with ...