With this innovation, the algorithm for searching for new proteins rapidly reduced its computational complexity, becoming non-linear through the spliceosome and the nucleus, which separated ...

A new study found that aged neurons have defects in key proteins that make them vulnerable to molecular stress and neurodegenerative damage.

Differentiated PH1 payload is a spliceosome inhibitor designed to inhibit RNA splicing, leading to cancer cell death and activation of immune system through multiple mechanisms. India represents a key ...

Autism symptoms and new approaches to treatment. Read current research on autism including early diagnosis of autism spectrum disorders, genetic factors and more.

Ten Indian American scientists were honored for their outstanding contributions in cancer research by the (SAASCR).

Decades of extensive research have determined the molecular pathways that direct seedling deetiolation. These studies have mainly focused on the transcriptional control of gene expression (Wu, 2014; ...

Our finding that the spliceosome deposits a multi‐protein complex 20‐‐24 nt upstream of exon–exon junctions on multiple mRNAs was unexpected. Not only is there is no consensus sequence in this region, ...

The spliceosome (SPL), a majestic machine composed of five small nuclear RNAs and hundreds of proteins, behaves as an ... SF3b1 plays a key role in recruiting the U2 snRNP to the BS. Mutations in ...

NB in the high-E2F group presented increased activity in the spliceosome, ATP-dependent chromatin remodeling, and other pathways related to genome regulation (Figures 7A, B). To analyze the tumor ...