The funds raised will be directed towards advancing Akari’s novel spliceosome inhibitor payload ... targets the TROP2 receptor and is designed to overcome limitations of current ADCs.

Akari’s lead candidate, AKTX-101, targets the TROP2 receptor and delivers a novel payload designed ... The private placement aims to advance Akari’s novel spliceosome inhibitor payload ADC technology ...

The funds raised will be directed towards advancing Akari’s novel spliceosome inhibitor payload ADC technology ... Akari’s lead candidate, AKTX-101, targets the TROP2 receptor and is designed to ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins ...