Model Context Protocol (MCP) is an open-source standard developed by Anthropic, the company behind the Claude AI chatbot. MCP allows AI models to connect to external data, read them, and execute ...

Spliceosome structures have been investigated extensively in the past decade, but most of the studies have been restricted to a handful of model organisms. New research by Lu et al, looks outside this ...

It was known that the spliceosome has quality control mechanisms, but the mechanistic details were not understood. For their experiments, the Heidelberg researchers led by BZH director Prof. Dr ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Heidelberg University. "Spliceosome: How cells avoid errors when manufacturing mRNA." ScienceDaily. ScienceDaily, 7 February 2025. <www.sciencedaily.com / releases / 2025 / 02 / 250207122612.htm>.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

After a decade of work, scientists have completed a molecular model of the human spliceosome, an incredibly complex cellular machine. When an active gene is expressed in a cell, it is transcribed into ...

Plants have a sophisticated mechanism for monitoring the production of new proteins. The U1 snRNP complex ensures that the protein blueprints are fully completed. This is important because cells tend ...

Journal Reference: Dimitrije Stanković, Luke S Tain, Mirka Uhlirova. Xrp1 governs the stress response program to spliceosome dysfunction. Nucleic Acids Research, 2024; DOI: 10.1093/nar/gkae055 ...