Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

Emerging evidence suggests that some variants, which are described as missense, synonymous or nonsense variants in the literature or databases, may be deleterious by affecting the pre-mRNA splicing ...

Proper splicing requires efficient spliceosome assembly ... a key component of nonsense-mediated mRNA decay (NMD), during cellular senescence and its impact on NMD efficiency, leading to the ...

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Varvara Dikaya's research sheds light on an essential part of this puzzle: RNA splicing, a process that ... this protein is part of the spliceosome, a molecular complex that modifies RNA before ...

Spliceosome structures have been investigated extensively in the past decade, but most of the studies have been restricted to a handful of model organisms. New research by Lu et al, looks outside this ...

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering ...

In magnetic systems, angular momentum is carried by spin and orbital degrees of freedom. Nonlocal devices, comprising heavy-metal nanowires on magnetic insulators like yttrium iron garnet (YIG), ...