Quality assurance in the cell: Preventing defective protein blueprints
Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...
Technology Networks8d
Structural Insights Into the Cell's Quality Control Machinery
They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...
eLife15d
Generative modeling for RNA splicing predictions and design
TrASPr is an important contribution that leverages transformer models focused on regulatory regions to enhance predictions of tissue-specific splicing events. The evidence supporting the authors' ...
Frontiers17d
Identified five variants in CFTR gene that alter RNA splicing by minigene assay
Emerging evidence suggests that some variants, which are described as missense, synonymous or nonsense variants in the literature or databases, may be deleterious by affecting the pre-mRNA splicing ...
Nature18d
RNA quality control articles from across Nature Portfolio
Proper splicing requires efficient spliceosome assembly ... a key component of nonsense-mediated mRNA decay (NMD), during cellular senescence and its impact on NMD efficiency, leading to the ...
C&EN24d
Phase Change-Mediated Capture of Carbon Dioxide from Air with a Molecular Triamine Network Solid
Institute for Decarbonization Materials, University of California, Berkeley, California 94720, United States Department of Chemistry, University of California, Berkeley, California 94720, United ...
Phys.org29d
The protein that helps plants survive the cold
Varvara Dikaya's research sheds light on an essential part of this puzzle: RNA splicing, a process that ... this protein is part of the spliceosome, a molecular complex that modifies RNA before ...